Interesting finding on COVID mortality in vaccinated people.

[Valcazar]

Study came out on molnupiravir in vaccinated patients.

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

Molnupiravir did not reduce the frequency of COVID-19-associated hospitalisations or death among high-risk vaccinated adults in the community.

www.thelancet.com

Summary of result: Molnupiravir did not reduce the frequency of COVID-19-associated hospitalisations or death among high-risk vaccinated adults in the community.
It did seem to lead to faster recovery.

That's a lot less impressive than the great results it was getting last year.

That said, Dr Jeremy Faust notes that the study provides some interesting information on COVID mortality among the vaccinated because this seems to be the first major study where both arms were vaccinated.

Covid-19 antiviral Molnupiravir not effective in preventing hospitalization and death among vaccinated patients with high risks.

Merck's drug improved recovery times, but failed to show benefit for its primary purpose. Still, this new study contains an unexpected trove of other good news.

insidemedicine.substack.com

I'll let him sum up in his twitter thread.

https://twitter.com/i/web/status/1606070316467249152

https://twitter.com/i/web/status/1606072353451954176

 

[squeezer]

Study came out on molnupiravir in vaccinated patients.

OH NO, I can hear the anti-vaxxers screaming and jumping up and down!!

3, 2, 1

 

[The Oracle]

Effectiveness of the Coronavirus Disease 2019 (COVID-19) Bivalent Vaccine

Background The purpose of this study was to evaluate whether a bivalent COVID-19 vaccine protects against COVID-19. Methods Employees of Cleveland Clinic in employment on the day the bivalent COVID-19 vaccine first became available to employees, were included. The cumulative incidence of...

www.medrxiv.org

'' The risk of COVID-19 also varied by the number of COVID-19 vaccine doses previously received. The higher the number of vaccines previously received, the higher the risk of contracting COVID-19 ''

'' The association of increased risk of COVID-19 with higher numbers of prior vaccine doses in our study, was unexpected. A simplistic explanation might be that those who received more doses were more likely to be individuals at higher risk of COVID-19. A small proportion of individuals may have fit this description. However, the majority of subjects in this study were generally young individuals and all were eligible to have received at least 3 doses of vaccine by the study start date, and which they had every opportunity to do. … This is not the only study to find a possible association with more prior vaccine doses and higher risk of COVID-19. … We still have a lot to learn about protection from COVID-19 vaccination, and in addition to a vaccine’s effectiveness it is important to examine whether multiple vaccine doses given over time may not be having the beneficial effect that is generally assumed. ''

 

[Valcazar]

Effectiveness of the Coronavirus Disease 2019 (COVID-19) Bivalent Vaccine

Background The purpose of this study was to evaluate whether a bivalent COVID-19 vaccine protects against COVID-19. Methods Employees of Cleveland Clinic in employment on the day the bivalent COVID-19 vaccine first became available to employees, were included. The cumulative incidence of...

www.medrxiv.org

'' The risk of COVID-19 also varied by the number of COVID-19 vaccine doses previously received. The higher the number of vaccines previously received, the higher the risk of contracting COVID-19 ''

'' The association of increased risk of COVID-19 with higher numbers of prior vaccine doses in our study, was unexpected. A simplistic explanation might be that those who received more doses were more likely to be individuals at higher risk of COVID-19. A small proportion of individuals may have fit this description. However, the majority of subjects in this study were generally young individuals and all were eligible to have received at least 3 doses of vaccine by the study start date, and which they had every opportunity to do. … This is not the only study to find a possible association with more prior vaccine doses and higher risk of COVID-19. … We still have a lot to learn about protection from COVID-19 vaccination, and in addition to a vaccine’s effectiveness it is important to examine whether multiple vaccine doses given over time may not be having the beneficial effect that is generally assumed. ''

It's an interesting study, and should be followed up on.
The main finding, of course, was that the bivalent vaccine is protective against the current variants - this was something else that came out of the multivariate analysis and not the purpose of the study.
As the paper states, it has been seen a couple of times before. (It isn't seen all the time, of course.)
Is it an artifact of the way the multivariate analysis was done? That's possible - Multivariate analysis like doesn't really look for interaction between the variables.

But right from the beginning there have been suspicions that grouping the shots too close together may make them less effective. They also didn't study whether multiple previous infections with COVID-19 had a risk factor associated with them, which they didn't gather in their data from what I can tell. (They would also need to look at multiple "exposures" to COVID-19 - people who had a combination of vaccines and infections.)

If we're lucky, they *did* gather that data and it just wasn't part of the initial study. I'd like to see if they can get into the time factor of these exposures as well, but I suspect that would be VERY hard to do.

 

[Addict2sex]

ER Doctor Shocks Panel with His New Data on Risks from Pfizer Vaccine | ...

 

[NotADcotor]

ER Doctor Shocks Panel with His New Data on Risks from Pfizer Vaccine | ...

Probably shocked the panel with his stupidity.

 

[sp free]

Booster-Caused IgG4 Immune Tolerance Explains Excess Mortality and "Chronic Covid"

Perhaps Giving Unproven Vaccines to Billions was a Bad Idea, After All

igorchudov.substack.com

 

[The Oracle]

ER Doctor Shocks Panel with His New Data on Risks from Pfizer Vaccine | ...

1 in 800 had serious adverse effects according to the Pfizer trial data. The polio vaccine runs about 1 in a million by comparison.

Of course Fauci et al won't be telling us that.

 

[basketcase]

1 in 800 had serious adverse effects according to the Pfizer trial data. The polio vaccine runs about 1 in a million by comparison.

Of course Fauci et al won't be telling us that.

Still with this shit? I guess the media is covering up the mass casualties from the billions of vaccinated people.