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Creatine may not build more muscle after all, study suggests

Vinson

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Nov 24, 2023
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It took them all these years to figure it out? Big Supplement companies are not going to be happy.

Sports supplement shown to ‘not make any difference’ at regular doses, researchers say

Creatine is a popular supplement used to help build muscle, but researchers in Australia are questioning its effectiveness.

Investigators from the University of New South Wales (UNSW) in Sydney found that individuals who took creatine while performing a three-month weightlifting regimen put on the same amount of muscle as those who did not take the supplement while lifting.

That’s according to their recent study, which was published in the journal Nutrients.

"We’ve shown that taking 5 grams of creatine supplement per day does not make any difference to the amount of lean muscle mass people put on while resistance training," senior author Mandy Hagstrom, PhD, an exercise scientist from UNSW’s School of Health Sciences, said in a news release about the study.

The clinical trial looked at 54 relatively healthy participants ranging from 18 to 50 years old who were divided into two groups.

Both groups completed the same 12-week resistance training, comprised of three supervised workouts a week.

The creatine group took the supplement one week prior to beginning the training regimen, referred to as a "wash-in," and continued taking the 5-gram dose each day for a total of 13 weeks while performing the exercise routine.

The control group received no creatine or placebo during the workout period.

"This is the first creatine study to utilize a wash-in phase, which is standard in other clinical trial designs," Hagstrom told Fox News Digital.

"This allows the effect of the creatine supplement to be separated from the effect of resistance training."

Previous trials have started supplementation and exercise programs on the same day, she noted, which made it difficult to determine the impact of each.

The researchers looked at lean muscle body mass in both groups at baseline, then after the seven-day wash-in and after completion of the 12-week weight-lifting program.


They used "dual-energy X-ray absorptiometry" — which is a non-invasive imaging technique — to measure bone mineral density and body composition.

While the creatine-supplemented group (particularly the women) showed about a one-pound gain in lean body mass compared to the non-supplemented group at the seven-day mark, both groups showed a 4.4-pound gain after performing the 12-week resistance training program.

There was no difference between the two groups when it came to lean body mass growth, according to the study.

"The people taking the creatine supplement saw changes before they even started exercising, which leads us to believe that it wasn’t actual real muscle growth, but potentially fluid retention," Hagstrom said.

Once the participants started exercising, they saw no additional benefit from creatine, she said — "which suggests that 5 grams per day is not enough if you’re taking it for the purposes of building muscle."

 

Massivo

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Sep 11, 2009
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It took them all these years to figure it out? Big Supplement companies are not going to be happy.

Sports supplement shown to ‘not make any difference’ at regular doses, researchers say

Creatine is a popular supplement used to help build muscle, but researchers in Australia are questioning its effectiveness.

Investigators from the University of New South Wales (UNSW) in Sydney found that individuals who took creatine while performing a three-month weightlifting regimen put on the same amount of muscle as those who did not take the supplement while lifting.

That’s according to their recent study, which was published in the journal Nutrients.

"We’ve shown that taking 5 grams of creatine supplement per day does not make any difference to the amount of lean muscle mass people put on while resistance training," senior author Mandy Hagstrom, PhD, an exercise scientist from UNSW’s School of Health Sciences, said in a news release about the study.

The clinical trial looked at 54 relatively healthy participants ranging from 18 to 50 years old who were divided into two groups.

Both groups completed the same 12-week resistance training, comprised of three supervised workouts a week.

The creatine group took the supplement one week prior to beginning the training regimen, referred to as a "wash-in," and continued taking the 5-gram dose each day for a total of 13 weeks while performing the exercise routine.

The control group received no creatine or placebo during the workout period.

"This is the first creatine study to utilize a wash-in phase, which is standard in other clinical trial designs," Hagstrom told Fox News Digital.

"This allows the effect of the creatine supplement to be separated from the effect of resistance training."

Previous trials have started supplementation and exercise programs on the same day, she noted, which made it difficult to determine the impact of each.

The researchers looked at lean muscle body mass in both groups at baseline, then after the seven-day wash-in and after completion of the 12-week weight-lifting program.


They used "dual-energy X-ray absorptiometry" — which is a non-invasive imaging technique — to measure bone mineral density and body composition.

While the creatine-supplemented group (particularly the women) showed about a one-pound gain in lean body mass compared to the non-supplemented group at the seven-day mark, both groups showed a 4.4-pound gain after performing the 12-week resistance training program.

There was no difference between the two groups when it came to lean body mass growth, according to the study.

"The people taking the creatine supplement saw changes before they even started exercising, which leads us to believe that it wasn’t actual real muscle growth, but potentially fluid retention," Hagstrom said.

Once the participants started exercising, they saw no additional benefit from creatine, she said — "which suggests that 5 grams per day is not enough if you’re taking it for the purposes of building muscle."

I never used creatine but my understanding was that it never made any claim to build more muscle... It's supposed to give your muscles more energy so you can lift more...

And it was well known that any increase in size was from fluid retention...

All in all, I'm not sure this study is any useful or that it says anything new...

Having said that I harbor a great deal of skepticism towards the supplement industry which could be made up of 50 to 75% snake oil...

It is a very lucrative industry, that's for sure...
 
Last edited:

csmitting

Well-known member
Aug 8, 2017
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Who ever said creatine builds muscle?

It naturally exists in your body. It’s a cellular energy source.. It works by increasing the availability of ATP (adenosine triphosphate), ie muscles & brain (unexpected benefit) have a little more energy to draw from.

The supplements increases the amount of Creatine in your system. The additional creatine is stored in muscle cells and holds more water which can make your muscles look fuller like you have a pump. It’s not uncommon for people to gain about +\- 5lbs of water (not muscle)

research is finding that there may (jury is still out) also be benefits to memory and mood.

but It will not increase muscle tissue like androgens or growth hormones.
 
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